{"id":5775,"date":"2021-11-24T08:48:32","date_gmt":"2021-11-24T08:48:32","guid":{"rendered":"https:\/\/www.herbalreality.com\/?post_type=herb&#038;p=5775"},"modified":"2026-03-02T10:56:42","modified_gmt":"2026-03-02T10:56:42","slug":"california-poppy","status":"publish","type":"herb","link":"https:\/\/www.herbalreality.com\/herb\/california-poppy\/","title":{"rendered":"California poppy"},"content":{"rendered":"","protected":false},"featured_media":5782,"parent":0,"menu_order":-230,"template":"","meta":{"_acf_changed":false,"footnotes":"","beyondwords_generate_audio":"1","beyondwords_integration_method":"rest-api","beyondwords_project_id":"47224","beyondwords_content_id":"3e992c7f-8132-405f-a812-38e25857ae7c","beyondwords_preview_token":"34bd9fdc-3ae6-43f2-a697-e7073f4e772a","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"tags":[531,50,179,532,106,49],"conditions":[696,694,685],"sustainability":[1576],"sense":[18,17,16,27],"western_action":[990,997,1001,1003,1018,1019],"chinese_action":[],"ayurvedic_action":[],"energetics_action":[1498,1497,1490,1494,1380],"writer":[],"region":[1893],"class_list":["post-5775","herb","type-herb","status-publish","has-post-thumbnail","hentry","tag-california-poppy","tag-insomnia","tag-nervous","tag-poppy","tag-sleep","tag-stress","conditions-nervous-system","conditions-cardiovascular-system","conditions-digestive-system","sustainability-green-sustainability-status","sense-bitter","sense-aromatic","sense-hot","sense-sweet","western_action-analgesic","western_action-antispasmodic","western_action-bitter","western_action-carminative","western_action-relaxant","western_action-sedative","energetics_action-bitter","energetics_action-pungent","energetics_action-relaxing","energetics_action-sweet","energetics_action-warm","region-western-herbs"],"acf":{"last_reviewed":"20251218","herb_author":null,"banner_text":"California poppy is a potent anxiolytic and analgesic","latin_name":"<em>Eschscholzia californica<\/em>","pseudonym_name":"","family_name":"Papaveraceae","herb_summary":"California poppy is a sedative herb that in smaller doses, helps to treat anxious states, whilst in larger doses can alleviate pain and promote sleep.","key_benefits":"Sedative\r\nAnxiolytic\r\nFor mild to moderate pain","how_does_it_feel":"<span style=\"font-weight: 400;\">A preparation of California poppy made by combination of infusion or tincture has a warmly aromatic odour. The initial taste is slightly sweet and warm, then a subsequent bitterness follows, as a result of the alkaloids. The initial sensation is one of immediate calm and relaxation as the warmth of the herb can be felt spreading throughout the body. <\/span>","hdif_image_1":5782,"hdif_image_2":6765,"hdif_image_3":5783,"hdif_video":"https:\/\/youtu.be\/u5dHbMGYfAw","sense":[17,18,16,27],"what_can_i_use_it_for":"[caption id=\"attachment_5782\" align=\"alignright\" width=\"516\"]<img class=\" wp-image-5782\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled-1000x667.jpg\" alt=\"California poppy (Eschscholzia californica)\" width=\"516\" height=\"344\" \/> California poppy (<em>Eschscholzia californica<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">California poppy is used to ease nervous tension and facilitate a feeling of relaxation in the mind and the body. As a <\/span><a href=\"https:\/\/www.herbalreality.com\/western-action\/sedative\/\"><span style=\"font-weight: 400;\">sedative<\/span><\/a><span style=\"font-weight: 400;\">, California poppy helps to promote sleep when taken in the evening before bed. It can be applied to support states of nervous exhaustion, and balance feelings of being tired and wired, often due to prolonged <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/stress-and-relaxation\/\"><span style=\"font-weight: 400;\">stress<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/burnout\/\"><span style=\"font-weight: 400;\">burnout<\/span><\/a><span style=\"font-weight: 400;\"> (1,2).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">This herb has both <\/span><a href=\"https:\/\/www.herbalreality.com\/western-action\/antispasmodic\/\"><span style=\"font-weight: 400;\">antispasmodic<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.herbalreality.com\/western-action\/nervine\/\"><span style=\"font-weight: 400;\">nervine<\/span><\/a><span style=\"font-weight: 400;\"> actions, California poppy may also\u00a0 be used to ease spasm in the digestive system and in the urinary tract. This may be applied in conditions such as irritable bowel syndrome (IBS) and enuresis (1,2).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Due to its antispasmodic and <\/span><a href=\"https:\/\/www.herbalreality.com\/western-action\/relaxant\/\"><span style=\"font-weight: 400;\">relaxant<\/span><\/a><span style=\"font-weight: 400;\"> actions, it is helpful in relieving muscular tension and aches. This may be best achieved by a combined approach using a tea made from the fresh flowers accompanied with a salve applied topically to the affected area. Those with spasmodic conditions associated with the nervous system such as neuralgia and neuropathy will also likely find benefit from using this herb regularly (3).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">California poppy has a calming effect on the nervous system, which also makes it useful to use during acute periods of anxiety or during panic attacks. With its gentle nervine relaxant effect, it may also be used for insomnia, restlessness and <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/migraine\/\"><span style=\"font-weight: 400;\">migraines<\/span><\/a><span style=\"font-weight: 400;\">.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It is non-addictive and safe for all ages including children. Its gently sedative effects can be especially helpful in treating colic, restlessness or pain in children (1\u20134).<\/span>","into_the_heart_of":"[caption id=\"attachment_5783\" align=\"alignright\" width=\"510\"]<img class=\" wp-image-5783\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-orange-flower-bloom-summer-scaled.jpg\" alt=\"California poppy (Eschscholzia californica)\" width=\"510\" height=\"340\" \/> California poppy (<em>Eschscholzia californica<\/em>)[\/caption]\r\n\r\nCalifornia poppy has a long tradition of use in Western herbal medicine for calming the nervous system and has been used for states of unrest such as insomnia, nervous agitation and mild to moderate pain. It can be used for any such presentations in children too, including over-excitability (5).\r\n\r\nCalifornia poppy is an excellent nervine that is energetically both cooling and relaxing. This combination of properties offers a perfect antidote to a hot and wired system. This herb may be indicated in hyperactive and agitated states of the nervous system. This plant can provide a calming and centering effect during times of stress, anxiety, depression or burnout (2). It can also be applied to calm the mind during anxious states, especially when repetitive thoughts are a strong feature in affecting peace or sleep.\r\n\r\nCalifornia poppy may be used for pain that interferes with sleep or for pain in the nerves such as is experienced in sciatica and shingles. This can be applied both topically and internally (1,2).\r\n\r\nCalifornia poppy is thought to have an affinity with the emotional heart. This is due to its dynamic combination of antihypertensive, antispasmodic and nervine actions. It is especially indicated when stress and anxiety affecting the nervous system manifest in the cardiovascular system, such as increased heart rate, mild chest pain and palpitations (1,2).\r\n\r\nIt can be used to gently relax these tensions, harmonising the mind to bring a sense of calm and serenity to the heart.","tradtional_uses":"<span style=\"font-weight: 400;\">California poppy has a long tradition of use in Western herbal medicine for calming the nervous system, being used for states of unrest such as insomnia, nervous agitation and mild to moderate pain (6).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It was used by Native Americans as a food, (the whole plant was cooked and eaten as a vegetable) and as a medicine in various preparations for both children and adults. Tribes from different parts of California used the plant in various ways and for a variety of conditions. The Mendocino used a root preparation applied to a painful tooth, taken for stomach aches or applied as a wash for headaches.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The Costanoan tribes used a decoction of the flowers to promote healthy sleep and as a preparation to be rubbed into hair to kill lice. The Chumash made a poultice of the seed pods to halt lactation in breast-feeding (7).<\/span>","what_practioners_say":"<h3><a href=\"https:\/\/www.herbalreality.com\/conditions\/nervous-system\"><span style=\"font-weight: 400;\"><img class=\" wp-image-6369 alignright\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2022\/02\/21124318\/Subcategory-Conditions-nervous-system-600x600.jpg\" alt=\"Nervous system\" width=\"446\" height=\"446\" \/>Nervous system<\/span><\/a><\/h3>\r\n<span style=\"font-weight: 400;\">California poppy is primarily used to support conditions affecting the nervous system including panic, anxiety, stress and pain. The desired effect is determined by the dose, with lower doses eliciting an anxiolytic effect, whilst higher doses become more sedative and analgesic (1,2).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It is a favoured remedy of many herbalists for use in minor aches and pains, especially if this is associated with nervous tension. It has a tradition of use for headaches and for colicky pains, so can help to ease cramps, spasms and is also useful for IBS. For overworked muscles, it can be taken in the form of a strong tea, and accompanied by an Epsom salt bath to ease soreness.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">California poppy can help to quieten an overactive mind, especially when recurring thoughts prevent sleep and rest. In cases where this is accompanied by physical sensations of anxiety such as spasm or pain, this herb is especially helpful (2,4). It is a safe and effective children's remedy that can be used as\u00a0 a sleep aid when there is anxiety, pain or over-excitability. Sources also suggest it can be used for bedwetting (1).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It is often included in a mix with other nervous system relaxants for a synergistic effect. It combines well with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/passionflower\/\"><span style=\"font-weight: 400;\">passionflower<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Passiflora incarnata<\/span><\/i><span style=\"font-weight: 400;\">) for hyperactivity, sleep disturbances and incessant rumination. It can also be combined with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/hops\/\"><span style=\"font-weight: 400;\">hops<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Humulus lupulus<\/span><\/i><span style=\"font-weight: 400;\">) and <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/valerian\/\"><span style=\"font-weight: 400;\">valerian<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Valeriana officinalis<\/span><\/i><span style=\"font-weight: 400;\">) to aid with insomnia and sleeplessness (8,9).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It can be mixed with another member of the poppy family \u2014 <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/corydalis\/\"><span style=\"font-weight: 400;\">corydalis<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Corydalis yanhusuo<\/span><\/i><span style=\"font-weight: 400;\">) to increase the analgesic effect and in combination with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/hawthorn\/\"><span style=\"font-weight: 400;\">hawthorn<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Crataegus monogyna<\/span><\/i><span style=\"font-weight: 400;\">) to ease anxiety, especially when cardiac symptoms are present (1,8).\u00a0<\/span>","research":"[caption id=\"attachment_304799\" align=\"alignright\" width=\"513\"]<img class=\" wp-image-304799\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/23115343\/California-poppy-Eschscholzia-californica-1000x667.jpg\" alt=\"California poppy (Eschscholzia californica)\" width=\"513\" height=\"342\" \/> California poppy (<em>Eschscholzia californica<\/em>)[\/caption]\r\n<h3>Alkaloids from <i>Eschscholzia californica<\/i> and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors <i>in vitro<\/i><\/h3>\r\n<span style=\"font-weight: 400;\">In this <\/span><i><span style=\"font-weight: 400;\">in vitro<\/span><\/i><span style=\"font-weight: 400;\"> study, a 70% ethanol extract of California poppy was able to bind to serotonin receptors 5-HT(1A) \u2014 these are responsible for neuromodulation, decreasing blood pressure and heart rate by blood vessel dilation and vagus nerve stimulation. The activity on the 5-HT(1A) receptor was at least partly due to the presence of the aporphine alkaloidN-methyllaurotetatanine (10).\u00a0<\/span>\r\n<h3>Modulatory effects of <i>Eschscholzia californica<\/i> alkaloids on recombinant GABAA receptors<\/h3>\r\n<span style=\"font-weight: 400;\">This preclinical study involved analysing the alkaloids from the aerial parts of <\/span><i><span style=\"font-weight: 400;\">Eschscholzia californica <\/span><\/i><span style=\"font-weight: 400;\">and their effect on human GABAa receptors. The study found (S)-reticuline alkaloids acted as a positive GABAa modulator. They concluded that the herb\u2019s sedative effects were due to (S)-reticuline alkaloids metabolising into morphine-like alkaloids acting at opioid receptors rather than direct GABAa binding. The study suggested using the herb in higher doses for stronger sedative effects (3).\u00a0<\/span>\r\n<h3>Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (<i>Crataegus oxyacantha<\/i> and <i>Eschscholtzia californica<\/i>) and magnesium in mild-to-moderate anxiety disorders<\/h3>\r\n<span style=\"font-weight: 400;\">In a double-blind randomised controlled trial a combination of California poppy, hawthorn (<\/span><i><span style=\"font-weight: 400;\">Crataegus oxycantha<\/span><\/i><span style=\"font-weight: 400;\">) and magnesium were compared to placebo to evaluate safety and efficacy of the combination on mild to moderate anxiety disorders. The trial was conducted amongst 264 adults diagnosed with mild-moderate generalised anxiety. Participants were divided into two groups, with one group (n=130) receiving the herbal extract, and the other (n=134) receiving placebo. The dosage given was two tablets twice a day for three months. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The Hamilton anxiety scale, somatic scores and change in patient self-assessment examined at day 7,14,30, 60 and 90 days after treatment showed that anxiety fell during treatment. The herbal treatment showed significant reductions in anxiety scores then placebo (p=0.005) suggesting these herbs can be effective in reducing anxiety (11).\u00a0<\/span>\r\n<h3>A combination of <i>Eschscholtzia californica<\/i> Cham. and <i>Valeriana officinalis<\/i> L. extracts for adjustment insomnia: A prospective observational study<\/h3>\r\n<span style=\"font-weight: 400;\">This open label, observational, longitudinal study was carried out in a French primary care setting to assess the effect of a supplement containing <\/span><i><span style=\"font-weight: 400;\">Eschscholzia californica <\/span><\/i><span style=\"font-weight: 400;\">and <\/span><i><span style=\"font-weight: 400;\">Valeriana officinalis<\/span><\/i><span style=\"font-weight: 400;\"> on individuals with insomnia. Thirty-six patients were included in the study, and were instructed to take up to four tablets per night over the course of four weeks. Each tablet contained 80 mg of <\/span><i><span style=\"font-weight: 400;\">Eschscholzia californica <\/span><\/i><span style=\"font-weight: 400;\">and 32 mg <\/span><i><span style=\"font-weight: 400;\">Valeriana officinalis<\/span><\/i><span style=\"font-weight: 400;\"> root extract. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Results showed that after one month insomnia severity was reduced (p&lt;0.0001), sleep duration had increased by 0.5 hours (p=0.002) and waking in the night was also reduced. Anxiety scores were also improved (p&lt;0.0001). This is a promising study for the use of California poppy in the treatment of anxiety and insomnia, however, more robust studies with a control group are warranted to further explore this herb (12).\u00a0<\/span>","did_you_know":"<span style=\"font-weight: 400;\">The opium poppy \u2013 <\/span><i><span style=\"font-weight: 400;\">Papaver somniferum<\/span><\/i><span style=\"font-weight: 400;\"> is renowned for possessing potent sedative properties. The opioids (alkaloids within the plant) are utilised by the medical profession in the production of codeine and morphine.\u00a0 As well as the strong sedative quality, morphine is an extremely powerful analgesic. California poppy is a far safer distant cousin. As it contains no morphine, it is a non-addictive, gentle option that is used in some programmes of opiate withdrawal (13,14).<\/span>","additional_information_right":{"illustration":261163},"additional_information_left":{"botany":"<i><span style=\"font-weight: 400;\">Eschscholzia californica<\/span><\/i><span style=\"font-weight: 400;\"> has finely pinnated (feathery) blue-green leaves and intense warm yellow-orange solitary 4-petalled flowers, silky in texture and having long stems. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The flowers close at night or in cold, windy weather. Slender, cylindrical ribbed seed capsules follow flowering, which split open rather explosively, spreading numerous small globular seeds up to six feet away. It is drought-tolerant and spreads well (15).<\/span>","common_names":"<ul>\r\n \t<li>California poppy<\/li>\r\n \t<li>Golden poppy<\/li>\r\n \t<li>Cup of Gold<\/li>\r\n<\/ul>","safety":"<span style=\"font-weight: 400;\">There is a lack of reliable information for the use of California poppy in pregnancy and lactation and, therefore, it should be avoided and only taken under the guidance of a medical herbalist (19).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It is wise to be very cautious when treating children with analgesic doses of this herb, (which tend to be higher than those that reduce anxiety). Use for the shortest possible time on the lowest effective dose for pain and titrate upwards incrementally in both the treatment of children and adults (1,4,5). If in doubt, seek the guidance of a qualified medical herbalist. <\/span>","interactions":"<span style=\"font-weight: 400;\">Theoretically, the alkaloids in California poppy may inhibit CYP3A4 enzymes; however, no interactions have yet been observed clinically and reported (3,18).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">California poppy has additive effects when used in conjunction with central nervous system (CNS) depressants (1,19).\u00a0 It also may bind to the same receptors as those targeted by certain antidepressants (SSRIs or MAO inhibitors), so caution is advised in these cases (19).<\/span>","contraindications":"<span style=\"font-weight: 400;\">None known (2,9,18)<\/span>","preparation":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Infusion\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tincture\u00a0<\/span><\/li>\r\n<\/ul>\r\n<span style=\"font-weight: 400;\">Preparations made from the fresh plant material are considered more potent, whether used as a tea or tincture.<\/span>","dosage":"<ul>\r\n \t<li aria-level=\"1\"><b>Tincture (1:10| 45%): <\/b><span style=\"font-weight: 400;\">2\u20134 ml three times daily. Drop doses can also be given.<\/span><\/li>\r\n<\/ul>\r\n<ul>\r\n \t<li aria-level=\"1\"><b>Fluid extract (1:1 | 25%):<\/b><span style=\"font-weight: 400;\"> 1\u20132 ml three times daily.\u00a0<\/span><\/li>\r\n<\/ul>\r\n<ul>\r\n \t<li aria-level=\"1\"><b>Infusion\/decoction:<\/b><span style=\"font-weight: 400;\"> 2\u20134 g up to three times daily (8,18).\u00a0<\/span><\/li>\r\n<\/ul>\r\n<ul>\r\n \t<li aria-level=\"1\"><b>Other preparations: <\/b><span style=\"font-weight: 400;\">1:5 in 25%, up to 4 ml per night for sleeplessness in children (1)<\/span><\/li>\r\n<\/ul>\r\n<span style=\"font-weight: 400;\">Dosages calculated from animal studies suggest that 1.5\u20136 g for a 60 kg adult in humans is required for a sedative effect, whilst dosages of between 25\u2013200 mg per kg for a more gentle anxiolytic effect (18). <\/span>","constituents":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Isoquinoline alkaloids:<\/strong> Californidine. sanguinarine, chelirubine, macarpine, chelerythrine,\u00a0 protopine, eschscholtzine, allocryptopine , (S)-Reticuline and N-methyllaurotetatanine<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Flavonoid glycosides:<\/strong> Occurring mainly as quercetin isorhamnetine glycosides, as well as kaempferol.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Phenolic acids:<\/strong> Caffeic and ferulic acids.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\">Fatty acids<\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Polysaccharides (8,18)<\/span><\/li>\r\n<\/ul>","plant_part_used":"<span style=\"font-weight: 400;\">Aerial parts <\/span>"},"habitat":"<span style=\"font-weight: 400;\">This graceful hardy annual, or perennial in warmer climates,\u00a0 is native to western North America and is the state flower of California. It has adapted to grow well in Mediterranean countries and grows well in the UK too, often cultivated for ornamental gardens. It is often found on grasslands and arid land, but is also found in coastal dunes, chaparral and coastal scrub, dry plains and coastal prairies, and the open slopes of pine or redwood forests (16).<\/span>","sustainability":"<span style=\"font-weight: 400;\">California poppy is classed as \u2018secure\u2019 on NatureServe Explorer, and is currently not listed on the IUCN Redlist (20,21).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">However, they state that the bigger threat to this plant is the genetic contamination of wild populations. This, coupled with the encroachment of human activities on the historic native habitat of this species is resulting in a largescale, human induced transformation in the distribution and genetic composition of this species (21,22).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Plant Serve also states that focusing on identifying and delineating good quality, native populations of this plant in its native habitats are some of the efforts needed to conserve the genetic strength of this species. They also state \u2018a conservation strategy should be developed to maintain some such high-quality occurrences in which the gene pool appears to be relatively undiluted by introduced stock, and in which the species is occupying its historic habitat\u2019 (21).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Read our article on <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/safety\/herbal-quality-safety-what-know-before-you-buy\/\"><span style=\"font-weight: 400;\">Herbal quality &amp; safety: What to know before you buy<\/span><\/a><span style=\"font-weight: 400;\">\u00a0and <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/western-herbal-medicine\/where-your-herbs-come-from\/\"><span style=\"font-weight: 400;\">Sustainable sourcing of herbs<\/span><\/a><span style=\"font-weight: 400;\"> to learn more about what to look for and questions to ask suppliers about sustainability.<\/span>","sustainability_content":"","sustainability_alternatives":"","quality_control":"<span style=\"font-weight: 400;\">California poppy is best used fresh as opposed to dried herb form to maximise the benefits from its constituents. It may also be tinctured from fresh herb as long as the alcohol percentage is high enough to account for the water content (22). <\/span>","how_to_grow":"<span style=\"font-weight: 400;\">California poppies are easy to grow. They prefer poor, well-drained soil in full sun and can be grown in exposed or coastal gardens, or in a mixed flower meadow.<\/span>\r\n<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sow in a drill spreading seeds thinly along the row. Use a trowel or your fingers to cover seeds very lightly with soil and water with a fine rose watering can.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sow seeds directly in situ where they are to flower between spring and autumn. These plants will suffer if moved.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thin seedlings out once they\u2019re about 4 cm tall and again at 8 cm, so that they\u2019re spaced about 15 cm apart.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Deadhead regularly to ensure a long flowering period (17).<\/span><\/li>\r\n<\/ul>","recipe":"<h3>California poppy tincture (using the whole fresh plant)<\/h3>\r\n<span style=\"font-weight: 400;\">It is always preferable to use plants harvested from intentional cultivation, and not to harvest wild specimens in order to protect local habitats. If there is an abundance however, they can be foraged from the wild, as long as some plant specimens are left to remain. Try to harvest when there are a combination of flowers and seed heads on the plant.<\/span>\r\n<h4>Ingredients<\/h4>\r\n<ul>\r\n \t<li><span style=\"font-weight: 400;\">1 litre 45% vodka\u00a0<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">300 g california poppy (fresh or dried)<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">2.4 litre kilner ja<\/span>r<\/li>\r\n<\/ul>\r\n<h4>How to make a California poppy tincture<\/h4>\r\n<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gently shake the aerial parts free of bugs and dust, and rinse the roots well if using them too.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cut into smallish chunks and put into a clean, wide-necked kilner jar gently packing down the herb and covering it with vodka so all the plant material is submerged.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Leave for a month, stirring the mixture once or twice daily.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Strain through a double layer of muslin and squeeze the plant material well to get as much liquid out as possible.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Try drop doses of between 40\u201380 drops (2\u20134 ml) either straight onto the tongue or diluted in a little water. Maximum daily dose: 6 ml of a 1:3 tincture.<\/span><\/li>\r\n<\/ul>\r\n<span style=\"font-weight: 400;\">This recipe is a 1:3, however more vodka may be required to top up the herb and it may end up being a 1:5 depending on how much extra liquid has been added.<\/span>","references":"<ol>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hoffmann D. <\/span><i><span style=\"font-weight: 400;\">Medical Herbalism: The Science and Practice of Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. Healing Arts Press; 2003.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mcintyre A. <\/span><i><span style=\"font-weight: 400;\">Complete Herbal Tutor : The Definitive Guide to the Principles and Practices of Herbal Medicine (Second Edition).<\/span><\/i><span style=\"font-weight: 400;\"> Aeon Books Limited; 2019.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fedurco M, Gregorov\u00e1 J, \u0160ebrlov\u00e1 K, et al. Modulatory effects of Eschscholzia californica alkaloids on recombinant GABAA receptors. <\/span><i><span style=\"font-weight: 400;\">Biochemistry Research International<\/span><\/i><span style=\"font-weight: 400;\">. 2015;2015:1-9. <\/span><a href=\"https:\/\/doi.org\/10.1155\/2015\/617620\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1155\/2015\/617620<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mcintyre A. <\/span><i><span style=\"font-weight: 400;\">Herbal Treatment of Children : Western and Ayurvedic Perspectives<\/span><\/i><span style=\"font-weight: 400;\">. Elsevier\/Butterworth-Heinemann; 2005.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bone K, Mills S. <\/span><i><span style=\"font-weight: 400;\">Principles and Practice of Phytotherapy: Modern Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2nd ed. Edinburgh Churchill Livingstone, Elsevier; 2013.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Association for the Advancement of Restorative Medicine (AARM). Poppy for Anxiety and Insomnia: Herbal Monographs from Restorative Medicine. Restorative Medicine. <\/span><a href=\"https:\/\/restorativemedicine.org\/library\/monographs\/california-poppy\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/restorativemedicine.org\/library\/monographs\/california-poppy\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Williams M, McKinsey E, Jenks A. California poppy. Herbalgram.org. Published 2025. Accessed December 17, 2025. <\/span><a href=\"https:\/\/www.herbalgram.org\/resources\/herbalgram\/issues\/141\/table-of-contents\/hg141-herbprofile-cali-poppy\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.herbalgram.org\/resources\/herbalgram\/issues\/141\/table-of-contents\/hg141-herbprofile-cali-poppy\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thomsen M. <\/span><i><span style=\"font-weight: 400;\">Phytotherapy Desk Reference<\/span><\/i><span style=\"font-weight: 400;\">. 6th ed. Aeon Books; 2022.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">American Botanical Council (ABC). German Commission E - California poppy. Herbalgram.org. Published 1991. Accessed October 10, 2024. <\/span><a href=\"https:\/\/www.herbalgram.org\/resources\/commission-e-monographs\/monograph-unapproved-component-characteristics\/california-poppy\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.herbalgram.org\/resources\/commission-e-monographs\/monograph-unapproved-component-characteristics\/california-poppy\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gafner S, Dietz BM, McPhail KL, et al. Alkaloids from <\/span><i><span style=\"font-weight: 400;\">Eschscholzia californica<\/span><\/i><span style=\"font-weight: 400;\"> and Their Capacity to Inhibit Binding of [<\/span><span style=\"font-weight: 400;\">3<\/span><span style=\"font-weight: 400;\">H]8-Hydroxy-2-(di-<\/span><i><span style=\"font-weight: 400;\">N<\/span><\/i><span style=\"font-weight: 400;\">-propylamino)tetralin to 5-HT<\/span><span style=\"font-weight: 400;\">1A<\/span><span style=\"font-weight: 400;\"> Receptors in Vitro. <\/span><i><span style=\"font-weight: 400;\">Journal of Natural Products<\/span><\/i><span style=\"font-weight: 400;\">. 2006;69(3):432-435. <\/span><a href=\"https:\/\/doi.org\/10.1021\/np058114h\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1021\/np058114h<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders. <\/span><i><span style=\"font-weight: 400;\">Current Medical Research and Opinion<\/span><\/i><span style=\"font-weight: 400;\">. 2003;20(1):63-71. <\/span><a href=\"https:\/\/doi.org\/10.1185\/030079903125002603\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1185\/030079903125002603<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdellah SA, Berlin A, Blondeau C, et al. A combination of Eschscholtzia californica Cham. and Valeriana officinalis L. extracts for adjustment insomnia: A prospective observational study. <\/span><i><span style=\"font-weight: 400;\">Journal of Traditional and Complementary Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2019;10(2):116-123. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.jtcme.2019.02.003\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.jtcme.2019.02.003<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rosner B, Neicun J, Yang JC, Roman-Urrestarazu A. Opioid prescription patterns in Germany and the global opioid epidemic: Systematic review of available evidence. Cheungpasitporn W, ed. <\/span><i><span style=\"font-weight: 400;\">PLOS ONE<\/span><\/i><span style=\"font-weight: 400;\">. 2019;14(8):e0221153. <\/span><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0221153\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1371\/journal.pone.0221153<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Zampieron ER. Successful application of Eschscholzia californica to combat opioid addiction. <\/span><i><span style=\"font-weight: 400;\">International Journal of Complementary &amp; Alternative Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2018;11(4). <\/span><a href=\"https:\/\/doi.org\/10.15406\/ijcam.2018.11.00403\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.15406\/ijcam.2018.11.00403<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">RHS. Eschscholzia californica | California poppy Annual Biennial\/RHS. Rhs.org.uk. Published 2025. Accessed August 1, 2025. <\/span><a href=\"https:\/\/www.rhs.org.uk\/plants\/106119\/eschscholzia-californica\/details\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.rhs.org.uk\/plants\/106119\/eschscholzia-californica\/details<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Becker A, Yamada Y, Sato F. California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism. <\/span><i><span style=\"font-weight: 400;\">Frontiers in Plant Science<\/span><\/i><span style=\"font-weight: 400;\">. 2023;14:1084358. <\/span><a href=\"https:\/\/doi.org\/10.3389\/fpls.2023.1084358\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.3389\/fpls.2023.1084358<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">BBC Gardeners World. How to grow California poppy. BBC Gardeners World Magazine. Published 2021. Accessed July 28, 2022. <\/span><a href=\"https:\/\/www.gardenersworld.com\/how-to\/grow-plants\/how-to-grow-california-poppy\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.gardenersworld.com\/how-to\/grow-plants\/how-to-grow-california-poppy\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fisher C. <\/span><i><span style=\"font-weight: 400;\">Materia Medica of Western Herbs<\/span><\/i><span style=\"font-weight: 400;\">. Aeon Books; 2018.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Natural Medicines Database. California poppy. Therapeuticresearch.com. Published 2025. Accessed December 18, 2025. <\/span><a href=\"https:\/\/naturalmedicines.therapeuticresearch.com\/Data\/ProMonographs\/California-Poppy#safety\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/naturalmedicines.therapeuticresearch.com\/Data\/ProMonographs\/California-Poppy#safety<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nature Serve Explorer. California poppy. Natureserve.org. Published 2025. Accessed May 1, 2025. <\/span><a href=\"https:\/\/explorer.natureserve.org\/Taxon\/ELEMENT_GLOBAL.2.160245\/Eschscholzia_californica\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/explorer.natureserve.org\/Taxon\/ELEMENT_GLOBAL.2.160245\/Eschscholzia_californica<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">IUCN. The IUCN Red List of Threatened Species. IUCN Red List of Threatened Species. Published 2019. <\/span><a href=\"https:\/\/www.iucnredlist.org\/search\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.iucnredlist.org\/search<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">California Species Field Guide. CA Species and Habitat Explorer. Mt.gov. Published 2025. Accessed December 18, 2025. <\/span><a href=\"https:\/\/fieldguide.mt.gov\/ca\/?species=eschscholzia%20californica\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/fieldguide.mt.gov\/ca\/?species=eschscholzia%20californica<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n<\/ol>","related_condition":[11797,135],"related_herb":[4934,13989],"related_article":[7793,13964],"new_template_switch":true,"herb_overview_content_one":"Not safe in pregnancy and lactation.\r\n\r\nAdditive effects when combined with other sedatives.","herb_overview_content_two":"Status: Low risk","herb_overview_content_three":"Isoquinoline alkaloids\r\nFlavonoids","herb_overview_content_four":"USA\r\nWild harvested and cultivated","herb_overview_content_five":"Sedative\r\nAnxiolytic\r\nNervine\r\nAntispasmodic","herb_overview_content_six":"Insomnia\r\nPain\r\nAnxiety\r\nHyperactivity","herb_overview_content_seven":"Cool\r\nDry","herb_overview_content_eight":"Aerial part\r\n12 g per day\r\nBetween 6\u201312 ml per day","botany":"<i><span style=\"font-weight: 400;\">Eschscholzia californica<\/span><\/i><span style=\"font-weight: 400;\"> has finely pinnated (feathery) blue-green leaves and intense warm yellow-orange solitary 4-petalled flowers, silky in texture and having long stems. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The flowers close at night or in cold, windy weather. Slender, cylindrical ribbed seed capsules follow flowering, which split open rather explosively, spreading numerous small globular seeds up to six feet away. It is drought-tolerant and spreads well (15).<\/span>","botanical_image":261163,"common_names":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">California poppy<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Golden poppy<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cup of gold<\/span><\/li>\r\n<\/ul>","herbal_preperation_image":304796,"preparation":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Infusion\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tincture\u00a0<\/span><\/li>\r\n<\/ul>\r\n<span style=\"font-weight: 400;\">Preparations made from the fresh plant material are considered more potent, whether used as a tea or tincture.<\/span>","plant_part_used":"<span style=\"font-weight: 400;\">Aerial parts <\/span>","dosage":"<ul>\r\n \t<li aria-level=\"1\"><b>Tincture (1:10| 45%): <\/b><span style=\"font-weight: 400;\">2\u20134 ml three times daily. Drop doses can also be given.<\/span><\/li>\r\n \t<li aria-level=\"1\"><b>Fluid extract (1:1 | 25%):<\/b><span style=\"font-weight: 400;\"> 1\u20132 ml three times daily<\/span><\/li>\r\n \t<li aria-level=\"1\"><b>Infusion\/decoction:<\/b><span style=\"font-weight: 400;\"> 2\u20134 g up to three times daily (8,18)<\/span><\/li>\r\n \t<li aria-level=\"1\"><b>Other preparations: <\/b><span style=\"font-weight: 400;\">1:5 in 25%, up to 4 ml per night for sleeplessness in children (1)<\/span><\/li>\r\n<\/ul>\r\n<span style=\"font-weight: 400;\">Dosages calculated from animal studies suggest that 1.5\u20136 g for a 60 kg adult in humans is required for a sedative effect, whilst dosages of between 25\u2013200 mg per kg for a more gentle anxiolytic effect (18). <\/span>","constituents":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Isoquinoline alkaloids:<\/strong> Californidine. sanguinarine, chelirubine, macarpine, chelerythrine,\u00a0 protopine, eschscholtzine, allocryptopine , (S)-Reticuline and N-methyllaurotetatanine<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Flavonoid glycosides:<\/strong> Occurring mainly as quercetin isorhamnetine glycosides, as well as kaempferol.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Phenolic acids:<\/strong> Caffeic and ferulic acids.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\">Fatty acids<\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Polysaccharides (8,18)<\/span><\/li>\r\n<\/ul>","recipe_image":6765,"safety_post":[6725],"safety":"<span style=\"font-weight: 400;\">There is a lack of reliable information for the use of California poppy in pregnancy and lactation and, therefore, it should be avoided and only taken under the guidance of a medical herbalist (19).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It is wise to be very cautious when treating children with analgesic doses of this herb, (which tend to be higher than those that reduce anxiety). Use for the shortest possible time on the lowest effective dose for pain and titrate upwards incrementally in both the treatment of children and adults (1,4,5). If in doubt, seek the guidance of a qualified medical herbalist. <\/span>","interactions":"<span style=\"font-weight: 400;\">Theoretically, the alkaloids in California poppy may inhibit CYP3A4 enzymes; however, no interactions have yet been observed clinically and reported (3,18).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">California poppy has additive effects when used in conjunction with central nervous system (CNS) depressants (1,19).\u00a0 It also may bind to the same receptors as those targeted by certain antidepressants (SSRIs or MAO inhibitors), so caution is advised in these cases (19).<\/span>","contraindications":"<span style=\"font-weight: 400;\">None known (2,9,18)<\/span>","sustainability_image_one":304798,"sustainability_image_two":304799,"faqs":null,"not_suitable_for":["Avoid in pregnancy and lactation","Drug interactions"]},"featured_image_urls_v2":{"full":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled.jpg",2560,1707,false],"thumbnail":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled-600x600.jpg",600,600,true],"medium":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled-1000x667.jpg",1000,667,true],"large":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled-1300x867.jpg",580,387,true],"banner_image":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled-1600x800.jpg",1600,800,true],"gform-image-choice-sm":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled.jpg",300,200,false],"gform-image-choice-md":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled.jpg",400,267,false],"gform-image-choice-lg":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2021\/11\/21124535\/Eschscholzia-californica-Cham-california-poppy-flowers-leaves-bloom-orange-scaled.jpg",600,400,false]},"post_excerpt_stackable_v2":"","category_list_v2":"","author_info_v2":{"name":"","url":""},"comments_num_v2":"0 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