{"id":273,"date":"2020-07-01T10:09:10","date_gmt":"2020-07-01T09:09:10","guid":{"rendered":"http:\/\/84.18.216.250\/~herbalreality\/?post_type=herb&#038;p=273"},"modified":"2026-01-23T09:13:56","modified_gmt":"2026-01-23T09:13:56","slug":"artichoke","status":"publish","type":"herb","link":"https:\/\/www.herbalreality.com\/herb\/artichoke\/","title":{"rendered":"Globe artichoke"},"content":{"rendered":"","protected":false},"featured_media":282788,"parent":0,"menu_order":500,"template":"","meta":{"_acf_changed":false,"footnotes":"","beyondwords_generate_audio":"1","beyondwords_integration_method":"rest-api","beyondwords_project_id":"47224","beyondwords_content_id":"81d4bb29-afde-49fa-b8b1-3e9262531f21","beyondwords_preview_token":"541a5f8b-6c6d-4ff7-b4d0-ee035d56c46e","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"tags":[38,40,41,42,39,44,43],"conditions":[685,694],"sustainability":[1576],"sense":[18,786],"western_action":[1004,1823,1001,2062,1008,1013,1014],"chinese_action":[],"ayurvedic_action":[],"energetics_action":[1498,1382,1487],"writer":[],"region":[1893],"class_list":["post-273","herb","type-herb","status-publish","has-post-thumbnail","hentry","tag-artichoke","tag-artichoke-leaf","tag-bitter","tag-digestion","tag-globe-artichoke","tag-hangover","tag-indigestion","conditions-digestive-system","conditions-cardiovascular-system","sustainability-green-sustainability-status","sense-bitter","sense-cooling","western_action-cholagogue-and-choleretic","western_action-antihyperlipidaemic","western_action-bitter","western_action-digestive-tonic","western_action-diuretic","western_action-hepatic","western_action-hepatoprotective","energetics_action-bitter","energetics_action-cool","energetics_action-dry","region-western-herbs"],"acf":{"last_reviewed":"20250112","herb_author":null,"banner_text":"Globe artichoke is used both as a vegetable and as a key liver remedy","latin_name":"<em>Cynara scolymus<\/em>","pseudonym_name":"","family_name":"Asteraceae","herb_summary":"The leaves of artichoke have a well established reputation for stimulating bile flow, restoring liver function and lowering cholesterol.","key_benefits":"Nausea and indigestion\r\nImproving digestion\r\nConstipation\r\nBile and gallbladder problems\r\nAs a detox remedy\r\nHigh cholesterol and metabolic syndrome","how_does_it_feel":"<span style=\"font-weight: 400;\">Artichoke can be found growing in allotments and gardens around the UK in the summer. Upon chewing a bit of the leaf, tasting a liquid extraction, the earthy bitterness is the first noticeable flavour. The fresh leaf is also used as a vegetable, with its warm earthy tones, similar to a root-like taste. However there is a lingering, almost comforting bitter aftertaste denoting its powerful bitter quality and action on the liver. The bitter taste becomes concentrated on drying.<\/span>","hdif_image_1":1980,"hdif_image_2":1982,"hdif_image_3":282789,"hdif_video":"https:\/\/www.youtube.com\/watch?v=3wKLwfenV-M","sense":[18,786],"what_can_i_use_it_for":"[caption id=\"attachment_1980\" align=\"alignright\" width=\"512\"]<img class=\" wp-image-1980\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21125920\/artichoke-3386681_1920-1000x668.jpg\" alt=\"Artichoke (Cynara scolymus)\" width=\"512\" height=\"342\" \/> Artichoke (<em>Cynara scolymus<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Artichoke leaf is a <\/span><a href=\"https:\/\/www.herbalreality.com\/western-action\/hepatic\/\"><span style=\"font-weight: 400;\">hepatic<\/span><\/a><span style=\"font-weight: 400;\"> remedy, acting on the liver by increasing bile and supporting digestion. It can be considered for those whose diet is rich in fatty foods or alcohol as it helps to effectively facilitate the breakdown of fat (1,2).\u00a0 It will often safely relieve biliary problems like recurrent gallbladder pains. This herb has a reputation for being used to relieve hangovers after overindulgence in alcohol, most likely due to its notable impact on bile production and liver metabolism (3).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Artichoke can be considered if cases of <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/constipation-and-digestive-detoxification\/\"><span style=\"font-weight: 400;\">constipation<\/span><\/a><span style=\"font-weight: 400;\"> which have not improved with the usual laxative remedies. As a <\/span><a href=\"https:\/\/www.herbalreality.com\/western-action\/cholagogue-and-choleretic\/\"><span style=\"font-weight: 400;\">choleretic<\/span><\/a><span style=\"font-weight: 400;\">, artichoke stimulates the production of bile, and its cholagogue action promotes the flow of bile into the intestine. Bile helps to stimulate peristalsis and soften stools, allowing for easier passage without the irritant quality of stimulant laxatives (2,4).\u00a0\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Due to its effect on lipid metabolism, artichoke can be applied for more long term use to reduce hyperlipidaemia. This indicates it in the treatment of <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/high-cholesterol\/\"><span style=\"font-weight: 400;\">high cholesterol<\/span><\/a><span style=\"font-weight: 400;\">, obesity and diabetes. Its hepatic actions make it useful in the treatment of metabolic syndrome as it helps to improve phase I and II liver metabolism, which are often impaired and contribute to disease severity in metabolic syndrome (2,4).\u00a0<\/span>","into_the_heart_of":"[caption id=\"attachment_8184\" align=\"alignright\" width=\"519\"]<img class=\" wp-image-8184\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21123610\/artichoke-fruit-and-flower-Cynara-scolymus-scaled.jpg\" alt=\"Artichoke (Cynara scolymus)\" width=\"519\" height=\"346\" \/> Artichoke (<em>Cynara scolymus<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Artichoke is first a liver and bile remedy, and it can be applied to relieve \u2018liverish\u2019 conditions or \u2018crise de foie\u2019 which typically present as slow, sluggish or depressed states (5,6).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Artichoke\u2019s primary actions are through its cooling bitter properties. The actions of bitter herbs are primarily via promoting detoxification through the liver, and thus improving the quality of blood (6). The liver is responsible for metabolising hormones, drugs and fats, and is a key eliminatory organ in the body. Providing effective liver support is an important consideration across many conditions, and artichoke acts as an effective clearing herb (5,6).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The cooling energetics of this plant help to cool excess liver heat, something which is often associated with anger or irritation (5). Energetically, it can be seen to reduce thickness, heaviness or sluggishness as it relieves stagnation and helps to drain dampness from the body (5,6). This cooling quality also extends to relieving hot, congested\u00a0 or inflammatory states including chronic inflammation and disease. These same actions can be thought of with its effect on cholesterol\u2014 clearing, moving congestion and metabolising. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Artichoke can be thought of to help those who carry extra emotional weight, and may have difficulty letting go. This may also manifest with suppressed anger or frustration. Artichoke helps to clear these excess emotions, providing clarity and a feeling of lightness (4).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">As with other traditional bitter remedies like <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/dandelion\/\"><span style=\"font-weight: 400;\">dandelion<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Taraxacum officinale<\/span><\/i><span style=\"font-weight: 400;\">), there is a simultaneous diuretic effect. This helps to facilitate the removal of toxic metabolites from the body through the urine (3).<\/span>","tradtional_uses":"<span style=\"font-weight: 400;\">The medicinal properties of artichoke have been known since antiquity, and it was particularly prized in the 16th to 19th centuries. It enjoyed a revival in the 20th century, particularly in France. This revival was in conjunction with the idea that an overburdened liver would result in ill health, and many conditions were considered a liver crisis \u2018crise de foie\u2019 (2).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Artichoke was widely considered one of the most effective detox remedies, indicated in \u2018liverish\u2019, to include gallbladder and biliary problems, nausea, and difficulty in metabolising fats and alcohol. Skin problems were often linked with this range of causes and were also treated with artichoke leaf. It was an established medicine for jaundice and hepatitis (7,8).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">19th century Eclectic physicians in the USA used artichoke as a blood cleanser (depurative) for the treatment of rheumatism, gout, as well as jaundice. They also valued its diuretic properties and applied it to oedematous conditions, low urine production (oliguria) and urinary stones (2,8).<\/span>","what_practioners_say":"<h3><a href=\"https:\/\/www.herbalreality.com\/conditions\/digestive-system\"><span style=\"font-weight: 400;\"><img class=\" wp-image-6364 alignright\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2022\/02\/21124321\/Subcategory-Conditions-digestive-system-600x600.jpg\" alt=\"Digestive system\" width=\"444\" height=\"444\" \/>Digestive system<\/span><\/a><\/h3>\r\n<span style=\"font-weight: 400;\">Artichoke is a first choice for stimulating the production and release of\u00a0 bile from the liver through the bowel. Patients often report that their stools can become transiently more yellow after taking the remedy. It works by supporting liver function, rather than through a forceful stimulation, alleviating any strain on liver function. It can be used to relieve symptoms of liver stress or congestion, such as intolerance to fats and alcohol, or for biliary problems like gallstones or gallbladder inflammation, however it is contraindicated in biliary obstruction caution is advised in active gallstones\u00a0 (2,4,10). <\/span>\r\n\r\n<span style=\"font-weight: 400;\">An indication the body may be struggling to digest fats include pale, greasy or stools that are difficult to pass. Adequate bile helps to prevent this, and increases absorption of fat soluble nutrients as well as promoting peristalsis (11). As a hepatic, it supports\u00a0 metabolic dysfunction-associated steatotic liver disease (MASLD) as it helps to reduce hepatic fat and cholesterol accumulation (13).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Artichoke is an effective gentle bitter digestive remedy that can relieve many symptoms of upset digestion, notably nausea and vomiting (especially associated with rich, fatty food and alcohol consumption), constipation , flatulence, bloating and other symptoms of <\/span><a href=\"https:\/\/www.herbalreality.com\/health-lifestyle\/digestion-nutrition\/herbal-treatment-for-ibs\/\"><span style=\"font-weight: 400;\">IBS<\/span><\/a><span style=\"font-weight: 400;\"> (irritable bowel syndrome) (1,2,10). As a bitter it is also cooling and is appropriate for traditional \u2018damp-heat\u2019 patterns accompanied by yellow coating on the tongue, signs of liver distress, perhaps of inflammatory bowel problems and intolerance to heat and humidity (11). It has developed a reputation for being a prime remedy to aid recovery from hangovers (3,10).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Artichoke works effectively in a blend with other herbs, it can be combined with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/fennel\/\"><span style=\"font-weight: 400;\">fennel<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Foeniculum vulgare<\/span><\/i><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/mint\/\"><span style=\"font-weight: 400;\">peppermint<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Mentha piperita<\/span><\/i><span style=\"font-weight: 400;\">) or <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/chamomile\/\"><span style=\"font-weight: 400;\">chamomile<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Matricaria chamomilla<\/span><\/i><span style=\"font-weight: 400;\">) for dyspepsia, bloating, flatulence or general abdominal discomfort (1,3). To treat constipation, it partners well with herbs with a stronger laxative and alterative action including <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/dandelion\/\"><span style=\"font-weight: 400;\">dandelion<\/span><\/a><span style=\"font-weight: 400;\"> root (<\/span><i><span style=\"font-weight: 400;\">Taraxacum officinale<\/span><\/i><span style=\"font-weight: 400;\">), burdock root (<\/span><i><span style=\"font-weight: 400;\">Artium lappa<\/span><\/i><span style=\"font-weight: 400;\">) or <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/yellow-dock\/\"><span style=\"font-weight: 400;\">yellow dock <\/span><\/a><span style=\"font-weight: 400;\">root (<\/span><i><span style=\"font-weight: 400;\">Rumex crispus<\/span><\/i><span style=\"font-weight: 400;\">) (1,3).\u00a0\u00a0<\/span>\r\n<h3><span style=\"font-weight: 400;\">Metabolic and inflammatory<\/span><\/h3>\r\n<span style=\"font-weight: 400;\">Artichoke can form part of a treatment protocol for the treatment of metabolic syndrome. It helps to lower lipid levels which indirectly help to improve insulin sensitivity. Dyslipidaemia is a defining feature of metabolic syndrome, thus artichoke is well placed to lower cholesterol and triglycerides (14,15).\u00a0<\/span>\r\n<h3><a href=\"https:\/\/www.herbalreality.com\/conditions\/cardiovascular-system\"><span style=\"font-weight: 400;\">Cardiovascular system<\/span><\/a><\/h3>\r\n<span style=\"font-weight: 400;\">Artichoke is known to support cardiometabolic support through its action on reducing dyslipidaemic factors contributing to <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/high-blood-pressure\/\"><span style=\"font-weight: 400;\">hypertension<\/span><\/a><span style=\"font-weight: 400;\"> and cardiovascular disease (16). By reducing cholesterol levels, this can prevent atherosclerosis and arteriosclerosis by preventing endothelial damage and dysfunction (17). It helps to reduce oxidative stress within the endothelium and manage chronic low grade inflammation helping to indirectly support cardiometabolic factors (2,17).\u00a0<\/span>","research":"[caption id=\"attachment_1981\" align=\"alignright\" width=\"521\"]<img class=\" wp-image-1981\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21125919\/artichoke-5404499_1920.jpg\" alt=\"Artichoke (Cynara scolymus)\" width=\"521\" height=\"347\" \/> Artichoke (<em>Cynara scolymus<\/em>)[\/caption]\r\n<h3>Effects of artichoke on blood pressure: A systematic review and meta-analysis<\/h3>\r\nThis systematic review and meta-analysis examined the effects of artichoke supplementation on blood pressure. Data was gathered from eight randomised controlled trials (RCTs), comprising adult men and women, generally middle-aged, with either diagnosed hypertension or non-alcoholic fatty liver disease (NAFLD). Participants received artichoke leaf supplementation (dosages varied across trials, typically standardised extracts) or placebo for 8\u201312 weeks.\r\n\r\nPrimary outcomes included changes in systolic blood pressure (SBP) and diastolic blood pressure (DBP). Results showed showed no significant effect of artichoke supplementation on SBP (WMD \u22120.77 mmHg, 95% CI \u22122.76 to 1.22) or DBP (WMD \u22120.11 mmHg, 95% CI \u22121.72 to 1.50) compared with placebo. However, subgroup analysis demonstrated that in hypertensive patients, artichoke supplementation significantly reduced SBP (WMD \u22123.19 mmHg, 95% CI \u22123.32 to \u22123.06) and DBP (WMD \u22122.33 mmHg, 95% CI \u22122.23 to \u22122.43), whereas no blood-pressure-lowering effect was observed in NAFLD patients. Additionally, interventions lasting 12 weeks significantly reduced DBP compared to the eight week treatment. The authors conclude that artichoke supplementation may offer modest but clinically relevant blood pressure reduction in hypertensive individuals, particularly with longer treatment times (16).\r\n<h3>Effect of <i>Cynara scolymus<\/i> L. on cardiometabolic outcomes: An updated meta-analysis of randomised controlled trials and meta-regression<\/h3>\r\nThis systematic review and meta-analysis explored the effect of artichoke on cardiometabolic outcomes including blood glucose, lipid levels, blood pressure, and anthropometrics. A total of 21 high quality RCTs were included covering a total of 1,372 participants between 20\u201360 years with conditions including hyperlipidaemia, metabolic syndrome, NAFLD, hypertension, or obesity. The treatment involved artichoke leaf extract or placebo with doses ranging from 50 to 2,700 mg\/day and durations between six weeks to six months.\r\n\r\nPrimary outcomes measured were fasting blood sugar (FBS), HbA1c, fasting insulin, HOMA-IR, LDL-C, HDL-C, total cholesterol (TC), triglycerides (TG), systolic\/diastolic blood pressure (SBP\/DBP), body weight (BW), and BMI and secondary outcomes included looking at liver enzymes. Results showed significant improvements in FBS (WMD \u22123.76 mg\/dL), fasting insulin (\u22121.35 mIU\/L), and HOMA-IR (\u22121.00), along with significant reductions in LDL-C (\u221212.94 mg\/dL), TC (\u221219.64 mg\/dL), and TG (\u221213.36 mg\/dL); SBP decreased modestly (\u22121.59 mmHg) when compared to placebo. Liver enzymes improved as secondary findings (AST \u22124.70 U\/L; ALT \u22123.72 U\/L). This study shows promising benefits of artichoke in the treatment of cardiometabolic dysfunction (17).\r\n<h3>Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose-response meta-analysis of randomized controlled trials<\/h3>\r\nThis updated systematic review and meta-analysis explored the effects of artichoke (<i>Cynara scolymus<\/i>) supplementation on lipid profiles. Data was analysed across 14 RCTs in participants with dyslipidaemia or related cardiovascular disease risk factors. Interventions included artichoke leaf extract or artichoke juice, with dosages ranging from 4\u201312 weeks. Primary outcomes included changes in triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C).\r\n\r\nResults showed that artichoke extract supplementation significantly reduced TG (WMD \u221217.01 mg\/dL), TC (WMD \u221217.01 mg\/dL), and LDL-C (WMD \u221217.48 mg\/dL), with no significant effect on HDL-C. In contrast, artichoke juice supplementation significantly reduced TG, TC, LDL-C, but was also associated with a reduction in HDL-C. Overall, the findings suggest that artichoke may help to prevent the risk of cardiovascular disease by improving lipid profiles (18).","did_you_know":"<span style=\"font-weight: 400;\">Artichoke leaf is widely favoured as one of the most effective treatments for hangovers (3). During the renaissance, and early modern Europe, the flower of artichoke was considered to provoke Venus and act as an aphrodisiac (19). <\/span>","additional_information_right":{"illustration":250049},"additional_information_left":{"botany":"<span style=\"font-weight: 400;\">Globe artichoke is a perennial plant in the Asteraceae (formerly Compositae), same as <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/milk-thistle\/\"><span style=\"font-weight: 400;\">milk thistle<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Silybum marianum<\/span><\/i><span style=\"font-weight: 400;\">), and is a cultivated hybrid of a thistle, probably <\/span><i><span style=\"font-weight: 400;\">Cynara cardunculus<\/span><\/i><span style=\"font-weight: 400;\"> L. It is a herbaceous plant which produces flowering stems of 1\u20132 m or more in length.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The basal, lobate-bipinnatisect leaves are very large, the stem leaves may be pinnatisect or entire.<\/span>\r\n\r\n<span style=\"font-weight: 400;\"> The leaves are grey-green to silver in colour and the underside is covered with a dense layering of fine hairs. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The inflorescence is formed of purplish-blue flowers grouped in heads which have an involucre of several long bracts which may be spiny. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The fruit is an oval achene with a plumed pappus (tuft of bristles) (20).<\/span>","common_names":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Globe artichoke<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">French artichoke<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cynara (Eng)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Artischocke<\/em> (Ger)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Artichaut<\/em> (Fr)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Artichiocco<\/em> (Ital)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Carciofo<\/em> (Ital)<\/span><\/li>\r\n<\/ul>","safety":"<span style=\"font-weight: 400;\">There is insufficient evidence for its safety during pregnancy and lactation, so is it best to consult a medical herbalist in these instances (2,24,25). There have been some reports of contact dermatitis, and allergic reactions after ingestion for some individuals (2,24,25).\u00a0 <\/span>","interactions":"<span style=\"font-weight: 400;\">Theoretically, artichoke could cause low blood glucose levels when used in conjunction with antidiabetic medication. It is recommended to monitor blood sugar levels closely to ensure no risk of hypoglycaemia (25). It may also cause low blood pressure when used in conjunction with antihypertensives, and close measurement is also advised (25). Artichoke might increase levels of drugs metabolised by CYP2B6 and decrease those metabolised by CYP2C19 (25). <\/span>","contraindications":"<span style=\"font-weight: 400;\">Contraindicated for those with a known allergy to plants of the Asteraceae family. Contraindicated in patients with obstructed bile ducts (1,2,4,24).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Caution is advised for those with gallstones, and it is recommended to consult a medical profession in this case. Avoid in intestinal spasm, hepatocellular disease, cholecystitis or hyperbilirubinaemia (1,2,4,24). <\/span>","preparation":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dried herb<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Powdered herb<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Capsule<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tincture<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid extract<\/span><\/li>\r\n<\/ul>","dosage":"<ul>\r\n \t<li><strong>Tincture (ratio 1:5 | 40%):<\/strong> Take 1\u20133 ml three times a day (2,23,24)<\/li>\r\n \t<li><strong>Infusion\/decoction:<\/strong> 1.5\u20136 g per day (for most therapeutic applications)<\/li>\r\n \t<li><strong>Other preparations:<\/strong> For treatment of high cholesterol, high doses are recommended of up to the equivalent of 4\u20139 g of dried leaf per day (2,23,24).<\/li>\r\n<\/ul>","constituents":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Sesquiterpene lactones (0.5 to 6%):<\/strong> Cynaropicrin (40 to 80% of the total), and cynarascolosides A, B and C<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Phenolic acids:<\/strong> Caffeic acid derivatives (polyphenols) chlorogenic acid (3-caffeoylquinic acid), cynarin (1,3-dicaffeoylquinic acid), and many other dicaffeoylquinic acid derivatives<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Flavonoids:<\/strong> Luteolin 7-0 glucoside, luteolin 7-0 rutinoside, luteolin, apigenin\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Polysaccharides<\/strong><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Phytosterols:<\/strong> Stigmasterol, campesterol, \u03b2-sitosterol (24)<\/span><\/li>\r\n<\/ul>","plant_part_used":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The immature flower of globe artichoke (not to be confused with Jerusalem artichoke)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Leaf<\/span><\/li>\r\n<\/ul>"},"habitat":"<span style=\"font-weight: 400;\">The globe artichoke is a perennial thistle originating in the Mediterranean, particularly around Italy, Sicily, Sardinia and parts of North Africa. It is typically found in open grasslands, scrub or grassland and is a common plant found growing in allotment to be harvested to be eaten as a delicious vegetable (20,21). <\/span>","sustainability":"Artichoke is a widely cultivated medicine, with no major threats to its growth or local environment. The medicinal leaves can be harvested from the plant without damaging the plant or its growth pattern (1,26,27).\r\n\r\n<span style=\"font-weight: 400;\">Read our article on <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/safety\/herbal-quality-safety-what-know-before-you-buy\/\"><span style=\"font-weight: 400;\">Herbal quality &amp; safety: What to know before you buy<\/span><\/a><span style=\"font-weight: 400;\">\u00a0and <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/western-herbal-medicine\/where-your-herbs-come-from\/\"><span style=\"font-weight: 400;\">Sustainable sourcing of herbs<\/span><\/a><span style=\"font-weight: 400;\"> to learn more about what to look for and questions to ask suppliers about sustainability.<\/span>","sustainability_content":"","sustainability_alternatives":"","quality_control":"<span style=\"font-weight: 400;\">Artichoke is predominantly cultivated rather than wild harvested, and due to it being a commercial crop, it risks being contaminated with a high amount of pesticides (23).<\/span>","how_to_grow":"<ol>\r\n \t<li style=\"font-weight: 400;\">Sow seeds either indoors or outside in March or April, 13 mm (\u00bdin) deep.<\/li>\r\n \t<li style=\"font-weight: 400;\">Transplant young plants to a warm sunny position in reasonably fertile, free-draining soil when they have at least five true leaves, spacing them 60\u201390 cm (2\u20133ft) apart. Later thinning out to leave the strongest seedling at each point. Water during dry weather and weed regularly. Seed-grown plants usually flower in their first summer.<\/li>\r\n \t<li style=\"font-weight: 400;\">In colder regions, cover plants in late autumn with a mulch of straw, compost or well-rotted manure, to protect them during cold winter weather.<\/li>\r\n \t<li style=\"font-weight: 400;\">Each spring, mulch with well-rotted manure or home-made compost, when the soil is warm and moist. Fertilise to improve flower production (22).<\/li>\r\n<\/ol>","recipe":"<h3>Digestive bitters<\/h3>\r\nThis digestive bitters mix can be taken to support digestive function and alleviate sluggish or slow digestion.\r\n<h4>Ingredients<\/h4>\r\n<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">20 ml artichoke tincture\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">20 ml <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/chamomile\/\"><span style=\"font-weight: 400;\">chamomile<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Matricaria chamomilla<\/span><\/i><span style=\"font-weight: 400;\">) tincture\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">20 ml <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/fennel\/\"><span style=\"font-weight: 400;\">fennel<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Foeniculum vulgare<\/span><\/i><span style=\"font-weight: 400;\">) tincture\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">20 ml <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/dandelion\/\"><span style=\"font-weight: 400;\">dandelion<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Taraxacum officinale<\/span><\/i><span style=\"font-weight: 400;\">) tincture\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">15 ml<\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/angelica\/\"><span style=\"font-weight: 400;\"> angelica<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Angelica archangelica<\/span><\/i><span style=\"font-weight: 400;\">) tincture\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">5 ml <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/gentian\/\"><span style=\"font-weight: 400;\">gentian<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Gentiana lutea<\/span><\/i><span style=\"font-weight: 400;\">) tincture\u00a0<\/span><\/li>\r\n<\/ul>\r\n<h4><span style=\"font-weight: 400;\">How to make a digestive bitter<\/span><\/h4>\r\n<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Combine all ingredients together in an amber bottle.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Label the bottle.\u00a0\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Take 1\u20135 ml before meals to aid digestion.\u00a0\u00a0<\/span><\/li>\r\n<\/ul>","references":"<ol>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mcintyre A. <\/span><i><span style=\"font-weight: 400;\">Complete Herbal Tutor : The Definitive Guide to the Principles and Practices of Herbal Medicine (Second Edition).<\/span><\/i><span style=\"font-weight: 400;\"> Aeon Books Limited; 2019.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bone K, Mills S. <\/span><i><span style=\"font-weight: 400;\">Principles and Practice of Phytotherapy: Modern Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2nd ed. Edinburgh Churchill Livingstone, Elsevier; 2013.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pittler MH, White AR, Stevinson C, Ernst E. Effectiveness of artichoke extract in preventing alcohol-induced hangovers: a randomized controlled trial. <\/span><i><span style=\"font-weight: 400;\">CMAJ: Canadian Medical Association Journal<\/span><\/i><span style=\"font-weight: 400;\">. 2003;169(12):1269. Accessed January 7, 2026. <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC280580\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC280580\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u00a0Hoffmann D. <\/span><i><span style=\"font-weight: 400;\">Medical Herbalism : The Science and Practice of Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. Healing Arts Press; 2003.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Wood M. <\/span><i><span style=\"font-weight: 400;\">The Practice of Traditional Western Herbalism : Basic Doctrine, Energetics, and Classification<\/span><\/i><span style=\"font-weight: 400;\">. North Atlantic Books, Cop; 2004.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hedley C, Shaw N. <\/span><i><span style=\"font-weight: 400;\">Plant Medicine<\/span><\/i><span style=\"font-weight: 400;\">. (Waddell G, ed.). Aeon Books; 2023.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Grieve M. A Modern Herbal | Artichoke, Globe. Botanical.com. Published 2025. Accessed January 7, 2026. <\/span><a href=\"https:\/\/botanical.com\/botanical\/mgmh\/a\/artic066.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/botanical.com\/botanical\/mgmh\/a\/artic066.html<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Culpeper N. <\/span><i><span style=\"font-weight: 400;\">The Complete Herbal<\/span><\/i><span style=\"font-weight: 400;\">. BoD \u2013 Books on Demand; 2018.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Majnooni MB, Ataee M, Bahrami G, et al. The effects of co\u2010administration of artichoke leaf extract supplementation with metformin and vitamin E in patients with nonalcoholic fatty liver disease: A randomized clinical trial. <\/span><i><span style=\"font-weight: 400;\">Phytotherapy Research<\/span><\/i><span style=\"font-weight: 400;\">. Published online September 17, 2021. <\/span><a href=\"https:\/\/doi.org\/10.1002\/ptr.7279\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1002\/ptr.7279<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thomsen M. <\/span><i><span style=\"font-weight: 400;\">Phytotherapy Desk Reference<\/span><\/i><span style=\"font-weight: 400;\">. 6th ed. Aeon Books; 2022.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Azer SA, Sankararaman S. Steatorrhea. Nih.gov. Published January 21, 2020. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541055\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541055\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Holmes P. <\/span><i><span style=\"font-weight: 400;\">The Energetics of Western Herbs : Treatment Strategies Integrating Western and Oriental Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. Snow Lotus Press; 2006.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Panahi Y, Kianpour P, Mohtashami R, et al. Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial. <\/span><i><span style=\"font-weight: 400;\">Phytotherapy Research<\/span><\/i><span style=\"font-weight: 400;\">. 2018;32(7):1382-1387. <\/span><a href=\"https:\/\/doi.org\/10.1002\/ptr.6073\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1002\/ptr.6073<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Silva H, Daia AM. Exploring the Cardiovascular Potential of Artichoke\u2014A Comprehensive Review. <\/span><i><span style=\"font-weight: 400;\">Biology<\/span><\/i><span style=\"font-weight: 400;\">. 2025;14(4):397-397. <\/span><a href=\"https:\/\/doi.org\/10.3390\/biology14040397\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.3390\/biology14040397<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Phimarn W, Sungthong B, Wichiyo K. Effect of <\/span><i><span style=\"font-weight: 400;\">Cynara scolymus<\/span><\/i><span style=\"font-weight: 400;\"> L. on Cardiometabolic Outcomes: An Updated Meta-analysis of Randomized Controlled Trials and Meta-regression. <\/span><i><span style=\"font-weight: 400;\">Pharmacognosy Magazine<\/span><\/i><span style=\"font-weight: 400;\">. 2024;20(2):372-388. <\/span><a href=\"https:\/\/doi.org\/10.1177\/09731296231217557\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1177\/09731296231217557<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moradi M, Sohrabi G, Golbidi M, et al. Effects of artichoke on blood pressure: A systematic review and meta-analysis. <\/span><i><span style=\"font-weight: 400;\">Complementary Therapies in Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2021;57:102668. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.ctim.2021.102668\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.ctim.2021.102668<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Amini MR, Sheikhhossein F, Alvani M, et al. Anti-hypertensive Effects of Artichoke Supplementation in Adults: A Systematic Review and Dose-response Meta-analysis of Randomized Controlled Trials. <\/span><i><span style=\"font-weight: 400;\">Clinical Nutrition Research<\/span><\/i><span style=\"font-weight: 400;\">. 2022;11(3):214. <\/span><a href=\"https:\/\/doi.org\/10.7762\/cnr.2022.11.3.214\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.7762\/cnr.2022.11.3.214<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shahinfar H, Bazshahi E, Amini MR, et al. Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose\u2013response meta\u2010analysis of randomized controlled trials. <\/span><i><span style=\"font-weight: 400;\">Phytotherapy Research<\/span><\/i><span style=\"font-weight: 400;\">. Published online September 27, 2021. <\/span><a href=\"https:\/\/doi.org\/10.1002\/ptr.7247\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1002\/ptr.7247<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">ABC Herbalgram. Artichoke. Herbalgram.org. Published 2026. Accessed January 9, 2026. <\/span><a href=\"https:\/\/www.herbalgram.org\/resources\/herbalegram\/volumes\/volume-17\/number-6-june\/food-as-medicine\/artichoke\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.herbalgram.org\/resources\/herbalegram\/volumes\/volume-17\/number-6-june\/food-as-medicine\/artichoke\/<\/span><\/a><span style=\"font-weight: 400;\">?\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">RHS. Cynara cardunculus Scolymus Group | globe artichoke Herbaceous Perennial\/RHS. Rhs.org.uk. Published 2024. Accessed December 7, 2024. <\/span><a href=\"https:\/\/www.rhs.org.uk\/plants\/56390\/cynara-cardunculus-scolymus-group\/details\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.rhs.org.uk\/plants\/56390\/cynara-cardunculus-scolymus-group\/details<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Royal Botanical Gardens Kew. Cynara cardunculus var. scolymus (L.) Benth. | Plants of the World Online | Kew Science. Plants of the World Online. Published 2025. Accessed January 9, 2026. <\/span><a href=\"https:\/\/powo.science.kew.org\/taxon\/urn:lsid:ipni.org:names:125755-3\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/powo.science.kew.org\/taxon\/urn:lsid:ipni.org:names:125755-3<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">RHS. How to grow globe artichokes \/ RHS Gardening. www.rhs.org.uk. Published 2025. <\/span><a href=\"https:\/\/www.rhs.org.uk\/vegetables\/globe-artichokes\/grow-your-own\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.rhs.org.uk\/vegetables\/globe-artichokes\/grow-your-own<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">European Medicines Agency. <\/span><i><span style=\"font-weight: 400;\">Assessment Report on Cynara Scolymus L., Folium <\/span><\/i><span style=\"font-weight: 400;\">.; 2011.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fisher C. <\/span><i><span style=\"font-weight: 400;\">Materia Medica of Western Herbs<\/span><\/i><span style=\"font-weight: 400;\">. Aeon Books; 2018.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Natural Medicines Database. Artichoke. Therapeuticresearch.com. Published 2025. <\/span><a href=\"https:\/\/naturalmedicines.therapeuticresearch.com\/Data\/ProMonographs\/Artichoke#safety\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/naturalmedicines.therapeuticresearch.com\/Data\/ProMonographs\/Artichoke#safety<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rana RL, Bux C, Lombardi M. Trends in scientific literature on the environmental sustainability of the artichoke (<\/span><i><span style=\"font-weight: 400;\">Cynara cardunculus<\/span><\/i><span style=\"font-weight: 400;\"> L. spp.) supply chain. <\/span><i><span style=\"font-weight: 400;\">British Food Journal<\/span><\/i><span style=\"font-weight: 400;\">. 2022;125(6):2315-2332. <\/span><a href=\"https:\/\/doi.org\/10.1108\/bfj-07-2022-0571\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1108\/bfj-07-2022-0571<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\">IUCN Redlist. The IUCN Red List of Threatened Species. IUCN Red List of Threatened Species. Published 2025. Accessed January 9, 2026. <a href=\"https:\/\/www.iucnredlist.org\/search?query=cynara%20scolymus&amp;searchType=species\" target=\"_blank\" rel=\"noopener\"><span>https:\/\/www.iucnredlist.org\/search?query=cynara%20scolymus&amp;searchType=species<\/span><\/a><\/li>\r\n<\/ol>","related_condition":[60873,198],"related_herb":[8126,3881],"related_article":[3761,8237],"new_template_switch":true,"herb_overview_content_one":"Not suitable during pregnancy or lactation\r\nCaution advised with gallstones and antihypertensives\r\nContraindicated in bile duct obstruction","herb_overview_content_two":"Low risk","herb_overview_content_three":"Sesquiterpene lactones\r\nPhenolic acids\r\nFlavonoids","herb_overview_content_four":"Country of origin\r\nWild harvested\/ cultivated\r\nAdulteration\/ contamination risks","herb_overview_content_five":"Bitter\r\nAntihyperlipidaemic\r\nAntihypertensive\r\nCholagogue","herb_overview_content_six":"High cholesterol\r\nSlow digestive function\r\nConstipation\r\nMetabolic syndrome","herb_overview_content_seven":"Cool\r\nDry\r\nBitter","herb_overview_content_eight":"Leaf\r\n1.5\u20136 g per day\r\n3\u20139 ml per day","botany":"<span style=\"font-weight: 400;\">Globe artichoke is a perennial plant in the Asteraceae (formerly Compositae), same as <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/milk-thistle\/\"><span style=\"font-weight: 400;\">milk thistle<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Silybum marianum<\/span><\/i><span style=\"font-weight: 400;\">), and is a cultivated hybrid of a thistle, probably <\/span><i><span style=\"font-weight: 400;\">Cynara cardunculus<\/span><\/i><span style=\"font-weight: 400;\"> L. It is a herbaceous plant which produces flowering stems of 1\u20132 m or more in length.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The basal, lobate-bipinnatisect leaves are very large, the stem leaves may be pinnatisect or entire.<\/span>\r\n\r\n<span style=\"font-weight: 400;\"> The leaves are grey-green to silver in colour and the underside is covered with a dense layering of fine hairs. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The inflorescence is formed of purplish-blue flowers grouped in heads which have an involucre of several long bracts which may be spiny. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The fruit is an oval achene with a plumed pappus (tuft of bristles) (20).<\/span>","botanical_image":250049,"common_names":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Globe artichoke<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">French artichoke<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cynara (Eng)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Artischocke<\/em> (Ger)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Artichaut<\/em> (Fr)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Artichiocco<\/em> (Ital)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><em>Carciofo<\/em> (Ital)<\/span><\/li>\r\n<\/ul>","herbal_preperation_image":282799,"preparation":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dried herb<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Powdered herb<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Capsule<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tincture<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid extract<\/span><\/li>\r\n<\/ul>","plant_part_used":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The immature flower of globe artichoke (not to be confused with Jerusalem artichoke)<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Leaf<\/span><\/li>\r\n<\/ul>","dosage":"<ul>\r\n \t<li><strong>Tincture (ratio 1:5 | 40%):<\/strong> Take 1\u20133 ml three times a day (2,23,24)<\/li>\r\n \t<li><strong>Infusion\/decoction:<\/strong> 1.5\u20136 g per day (for most therapeutic applications)<\/li>\r\n \t<li><strong>Other preparations:<\/strong> For treatment of high cholesterol, high doses are recommended of up to the equivalent of 4\u20139 g of dried leaf per day (2,23,24).<\/li>\r\n<\/ul>","constituents":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Sesquiterpene lactones (0.5 to 6%):<\/strong> Cynaropicrin (40 to 80% of the total), and cynarascolosides A, B and C<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Phenolic acids:<\/strong> Caffeic acid derivatives (polyphenols) chlorogenic acid (3-caffeoylquinic acid), cynarin (1,3-dicaffeoylquinic acid), and many other dicaffeoylquinic acid derivatives<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Flavonoids:<\/strong> Luteolin 7-0 glucoside, luteolin 7-0 rutinoside, luteolin, apigenin\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Polysaccharides<\/strong><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Phytosterols:<\/strong> Stigmasterol, campesterol, \u03b2-sitosterol (24)<\/span><\/li>\r\n<\/ul>","recipe_image":8183,"safety_post":[276784],"safety":"<span style=\"font-weight: 400;\">There is insufficient evidence for its safety during pregnancy and lactation, so is it best to consult a medical herbalist in these instances (2,24,25). There have been some reports of contact dermatitis, and allergic reactions after ingestion for some individuals (2,24,25).\u00a0 <\/span>","interactions":"<span style=\"font-weight: 400;\">Theoretically, artichoke could cause low blood glucose levels when used in conjunction with antidiabetic medication. It is recommended to monitor blood sugar levels closely to ensure no risk of hypoglycaemia (25). It may also cause low blood pressure when used in conjunction with antihypertensives, and close measurement is also advised (25). Artichoke might increase levels of drugs metabolised by CYP2B6 and decrease those metabolised by CYP2C19 (25). <\/span>","contraindications":"","sustainability_image_one":282786,"sustainability_image_two":1980,"faqs":null,"not_suitable_for":["Pregnancy & lactation","Drug interaction","Contraindications"]},"featured_image_urls_v2":{"full":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus.jpg",1497,998,false],"thumbnail":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus-600x600.jpg",600,600,true],"medium":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus-1000x667.jpg",1000,667,true],"large":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus-1300x867.jpg",580,387,true],"banner_image":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus-1497x800.jpg",1497,800,true],"gform-image-choice-sm":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus.jpg",300,200,false],"gform-image-choice-md":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus.jpg",400,267,false],"gform-image-choice-lg":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/23090101\/Globe-artichoke-Cynara-scolymus.jpg",600,400,false]},"post_excerpt_stackable_v2":"","category_list_v2":"","author_info_v2":{"name":"","url":""},"comments_num_v2":"0 comments","_links":{"self":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb"}],"about":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/types\/herb"}],"version-history":[{"count":10,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/273\/revisions"}],"predecessor-version":[{"id":282801,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/273\/revisions\/282801"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/posts\/276784"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/posts\/8237"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/posts\/3761"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/3881"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/8126"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/condition\/198"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/condition\/60873"}],"acf:term":[{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/786"},{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/18"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/media\/282788"}],"wp:attachment":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/media?parent=273"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/tags?post=273"},{"taxonomy":"conditions","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/conditions?post=273"},{"taxonomy":"sustainability","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sustainability?post=273"},{"taxonomy":"sense","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense?post=273"},{"taxonomy":"western_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/western_action?post=273"},{"taxonomy":"chinese_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/chinese_action?post=273"},{"taxonomy":"ayurvedic_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/ayurvedic_action?post=273"},{"taxonomy":"energetics_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/energetics_action?post=273"},{"taxonomy":"writer","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/writer?post=273"},{"taxonomy":"region","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/region?post=273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}